Journal Watch
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Care Partner Roles In-center and at Home
A multi-center longitudinal cohort study investigated caregiver responsibilities during the first year of in-center vs. home hemodialysis in 202 patient-caregiver dyads. Both groups experienced a decline in measures including depressive symptoms, physical and general health-related quality of life (HRQOL), and perceived health status. Caregiver burden and mental HRQOL did not change. The types of support desired by each group differed.
Read the abstract » | (added 2026-04-14)
Tags: Care Partner, HHD, Quality Of Life, Caregiver Burden
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Diabetes, Incremental PD, and Residual Kidney Function
A retrospective study analyzed 76 patients with diabetes, of whom 57.9% (44) started PD incrementally. Incremental PD significantly slowed the loss of residual kidney function (~60%) vs. full-dose PD and did not increase risk of transfer to hemodialysis or death. Overall, iPD appears safe and RRF-preserving, with glycemic control critical for outcomes.
Read the abstract » | (added 2026-04-14)
Tags: Diabetes, Incremental PD, Residual Kidney Function, Mortality
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Dry, Itchy Skin and Peritonitis on PD
Among 702 PD patients from two data sources, the risk of PD catheter-related infections rose among those with xerosis (hazard ratio 2.71; 95% confidence interval)—particularly S. aureus infections, which were higher in patients who had severe pruritus. Pet owners were also at risk for severe xerosis, as were those with higher serum creatinine levels and calcium-phosphorus products.
Read the abstract » | (added 2026-04-14)
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Lived Experience of Home Dialysis
A meta-analysis aimed at understanding the lived experiences of home dialysis patients identified 10 international studies (n=325 participants) and identified eight themes. The authors found that patients can feel both positively and negatively about home dialysis at the same time.
Read the abstract » | (added 2026-04-14)
Tags: Lived Experiences, Home Dialysis
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Chronic Inflammation and PD Outcomes
Among 111 PD patients stratified by C-reactive protein (CRP) into “normal” (<3mg/L) and “inflammation” (>3mg/dL) groups, the inflammation group had significant differences, including lower urine volume, hemoglobin, prealbumin, potassium, magnesium, and TSAT—but higher serum ferritin and WBC counts (p < 0.05). Systemic inflammation can interfere with nutrition, anemia treatment, and is linked with reduced residual kidney function.
Read the abstract » | (added 2026-04-14)
Tags: PD, C reactive Protein
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PD for Frail Seniors
For the frail elderly in the UK, PD offers quality of life, cognitive, and treatment satisfaction benefits over HD. Assisted PD can support those with physical or cognitive impairments and alleviate some caregiver burden. Improved funding and access to assisted PD programs are needed going forward to ensure PD is a viable treatment option.
Read the abstract » | (added 2026-04-14)
Tags: Quality Of Life, PD, Impairments, Burden
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Alternative Quality Metrics for Kt/V-free PD
This article explores the historic origins of Kt/V and its adaptation to PD and the limitations of using urea removal as a surrogate for other uremic toxins. Are residual kidney and dialytic urea clearances equivalent? Is urea distribution volume accurate? The authors don’t think so! They propose a shift away from Kt/V and “adequacy” to person-centered care.
Read the abstract » | (added 2026-04-14)
Tags: Kt/V, PD, Urea Removal, Person centered Care
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PD Patients Exhibit Cognitive Deficits but Not Ischemic Brain Injury
How does PD affect the brain? In this small imaging and cognitive study, researchers observed patterns of impairment and unexpected metabolic changes. The findings raise new questions about the neurological effects of PD that merit closer investigation.
Read the abstract » | (added 2026-03-12)
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Health Disparities in UK Kidney Replacement Therapy Modality Transitions
93,451 patients initiated KRT in England from 2005 to 2020. Compared with White patients, findings from Asian, Black, and patients in deprived areas demonstrated inequalities in the KRT pathway.
Read the abstract » | (added 2026-03-12)
Tags: KRT, Kidney Replacement Therapy, Modality Transitions, Ethnic Disparities
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Ultrasound-Guided Percutaneous PD Cather Insertion Technique to Reduce Migration
PD catheter migration can interrupt treatment and compromise outcomes, but it is challenging to prevent. In a two-center study, researchers examined whether adding musculofascial tunnelling during catheter insertion improves catheter stability.
Read the abstract » | (added 2026-03-12)