Journal Watch - Peritoneal Dialysis

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  1. Three Diuretics are Better than One on PD

    A small study (n=51) randomly assigned adult CAPD patients to receive three diuretics or just one plus placebo for 6 months. Among the 43 patients who completed the trial, those who took three diuretics had significantly better hydration status and more change in urine output—with no adverse events reported.

    Read the abstract » | (added 04/11/2019)

    Tags: Peritoneal Dialysis, Furosemide, Hydration Status, Hydrochlorothiazide, Spironolactone

  2. Home HD - Significantly Better Survival and Transplant Rate

    A Swedish matched cohort study compared the long-term survival of 152 home HD patients with those doing PD (n=456) or standard in-center HD (n=608). Median survival for home HD was significantly better (18.5 years) than PD (15.0) and in-center HD (11.9). Home HD patients were also significantly more likely to have received a transplant.

    Read the abstract » | (added 03/12/2019)

    Tags: Survival, Home Hemodialysis, Institutional Hemodialysis, Peritoneal Dialysis

  3. Impact of High Protein Diets on Residual Kidney Function in PD

    Does a high-protein diet cause a faster loss of residual kidney function for PD patients? An observational study of 336 patients for at least 6 months suggests that it may.

    Read the abstract » | (added 01/11/2019)

    Tags: Protein Intake, Residual Kidney, Peritoneal Dialysis, Pd

  4. Protein Clearance Predicts Mortality on PD

    Protein clearance on PD may be a marker of peritoneal inflammation. Among 711 PD patients followed for at least one year, each 10mL/day rise in protein clearance was linked with a 10.4% increase in the risk of all-cause mortality (p=0.008). Protein clearance was linked with serum albumin and C-reactive protein levels.

    Read the abstract » | (added 12/14/2018)

    Tags: Protein Clearance, Peritoneal Dialysis, Mortality

  5. Medicare Reimbursement Has Driven More PD

    Changes to the Medicare Prospective Payment System (PPS) in 2011 to create financial incentives for PD have worked, finds a new analysis of 6,433 dialysis clinics before and after the change. Since 2011, 6% more clinics offered PD, and program size increased from an average of 5.7 patients to 6.9. Non-urban, chain, and larger clinics were significantly more likely to have changed their PD practices in response to the PPS change.

    Read the abstract » | (added 12/14/2018)

    Tags: Medicare, Prospective Payment System, Peritoneal Dialysis, Quality Of Life

  6. Metaanalysis of PD for Kidney Failure due to PKD

    Polycystic kidneys may displace room for PD fluid, so can PD be a viable treatment option? A metaanalysis of 12 studies and more than 17,000 patients found…maybe. PD outcomes were about the same for those with PKD as with other primary kidney diseases, and some can do PD. More research is needed to determine who is suitable. Read the abstract.

    Read the abstract » | (added 10/12/2018)

    Tags: Dialysis Adequacy, Pd Associated Complications, Peritoneal Dialysis, Polycystic Kidney Disease

  7. Biocompatible PD Solutions Maintain Membranes Longer

    Independently of inflammation, biocompatible PD solutions helped 71 patients keep a steady level of solute transport over 7.5 years, compared to 295 patients who used standard solutions. Read the abstract.

    Read the abstract » | (added 09/10/2018)

    Tags: Dialysis Solutions, Glucans, Glucose, Il6 Protein, Human, Inflammation, Interleukin 6, Peritoneal Fibrosis, Peritoneum, Peritonitis, Creatinine, Hospitalization, Icodextrin, Peritoneal Dialysis, Peritoneal Membrane

  8. Gender and Malnutrition in PD

    Do hypoalbumineumia, overhydration, inflammation, and cardiovascular risk affect men and women on PD differently? A small study (N=26 men and 28 women) with comparable BMI found more fluid overload, inflammation, and heart risk in women with low serum albumin than in men. Read the abstract.

    Read the abstract » | (added 09/10/2018)

    Tags: Gender, Malnutrition, Cardiovascular Risk, Hypoalbuminemia, Inflammation, Overhydration, Peritoneal Dialysis

  9. Regional Variation in PD Infection Prevention

    A PDOPPS analysis of surveys from medical directors caring for more than 11,000 patients from 170 clinics in seven countries (Australia, New Zealand, Canada, Thailand, Japan, the UK, and the US) found variation from 63% to 100% in use of antibiotic prophylaxis for PD exit sites, with mupirocin used most often.

    Read the abstract » | (added 08/13/2018)

    Tags: Peritoneal Dialysis Related Infections, Peritoneal Dialysis, Infections, Peritoneal Dialysis Outcomes

  10. PD vs. In-Center HD for Stroke Risk

    A systematic review of 15 cohort studies totaling nearly 1.3M ESRD patients concludes that PD had a significantly lower (16%) risk of hemorrhagic stroke, though the risks of other types of strokes were comparable.

    Read the abstract » | (added 08/13/2018)

    Tags: Dialysis, Hemodialysis, Meta Analysis, Peritoneal Dialysis, Stroke